- 1 -

1-Exponential

1-Tissue Compartment Model

IconList of PKIN Compartment Models
Icon1-Tissue Compartment Model

- 2 -

2-Exponentials

2-Tissue Compartment Model

IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model

2-Tissue Compartment Model with Vascular Binding

2-Tissue Compartment Model with Vascular Trapping

IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model with Vascular Trapping

2-Tissue Compartment Model, Bmax

IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model, Bmax

2-Tissue Compartment Model, K1/k2

2-Tissue Compartment Model, K1/k2, Bmax

2-Tissue Compartment Model, K1/k2, Vs

2-Tissue Compartment Model, K1/k2, Vt

IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model, K1/k2, Vt

2-Tissue Compartment Model, k5

IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model, k5

2-Tissue Compartment Model, Linear Least Squares Method

IconFitting Options on Extras Panel
IconList of PKIN Compartment Models
Icon2-Tissue Compartment Model, Linear Least Squares Method

- 3 -

3-Exponentials

IconLinear Interpolation Fraction
Icon3-Exponentials

3-Tissue Compartment Model

IconList of PKIN Compartment Models
Icon3-Tissue Compartment Model
Icon3-Tissue Compartment Model, K1/k2, Vs

3-Tissue Compartment Model, K1/k2, Vs

IconList of PKIN Compartment Models
Icon3-Tissue Compartment Model, K1/k2, Vs

3-Tissue Compartment Model, Sequential

IconList of PKIN Compartment Models
Icon3-Tissue Compartment Model, Sequential

3-Tissue Compartments with Metabolites

IconList of PKIN Compartment Models
Icon3-Tissue Compartments with Metabolites
Icon3-Tissue Compartments with Metabolites, K1/k2
Icon3-Tissue Compartments with Metabolites, K1/k2, Vs

3-Tissue Compartments with Metabolites, K1/k2

IconList of PKIN Compartment Models
Icon3-Tissue Compartments with Metabolites, K1/k2

3-Tissue Compartments with Metabolites, K1/k2, Vs

IconList of PKIN Compartment Models
Icon3-Tissue Compartments with Metabolites, K1/k2, Vs

- 4 -

4-Tissue Compartments with Metabolites, K1/k2

IconList of PKIN Compartment Models
Icon4-Tissue Compartments with Metabolites, K1/k2

- A -

Analysis of Parameter Sensitivity and Identifiability

Area under Curve (AUC)

IconNon-Compartmental Models
IconArea under Curve (AUC)

Assessing Fit Results

IconProcessing Overview
IconAssessing Fit Results

Auxiliary Tools

- B -

Batch Mode

IconProcessing Overview
IconPKIN Menu
IconDefault Model Configurations and Configuration Sets
IconBatch Mode

Blood Delay Fitting

IconWhole Blood
IconFitting Options on Extras Panel
IconBlood Delay Fitting
IconWater PET Model with Flow and Dispersion
IconLinear Activity Interpolation
IconDecaying Exponentials
IconCompartment Model with 3 Eigenvalues
IconCompartment Model with 2 Eigenvalues
IconGamma Function
IconGamma Function plus two Decaying Exponentials

Bolus/Infusion Optimization

IconBolus/Infusion Optimization
IconSimulation of Bolus/Infusion Tracer Application

- C -

Calculation of the Model Curve

Calibration: Correction

Calibration: Step-Down

Calibration: Step-Up

Card. H2O (Geometrical corr.)

IconCompartment Models for Cardiac PET
IconCard. H2O (Geometrical corr.)

Card. NH3 (2 Compartments)

IconCompartment Models for Cardiac PET
IconCard. NH3 (2 Compartments)

Card. NH3 (2 Compartments, K1/k2)

IconCard. NH3 (2 Compartments)
IconCard. NH3 (2 Compartments, K1/k2)

Card. NH3 (de Grado)

IconCompartment Models for Cardiac PET
IconCard. NH3 (de Grado)

Card. NH3 (UCLA, 2 Parameters)

IconCompartment Models for Cardiac PET
IconCard. NH3 (UCLA, 2 Parameters)

Card. Rb-82 (1 Compartment)

IconCompartment Models for Cardiac PET
IconCard. Rb-82 (1 Compartment)

Card. Rb-82 (2 Compartments)

IconCompartment Models for Cardiac PET
IconCard. Rb-82 (2 Compartments)

Cardiac Flow from Acetate PET

IconCompartment Models for Cardiac PET
IconCardiac Perfusion from Acetate PET

Cardiac Flow from Ammonia PET

Cardiac Flow from Rubidium-82 PET

Cardiac Flow from Water PET

IconCompartment Models for Cardiac PET
IconCardiac Perfusion from Water PET

Changing Display Types

Comments

IconComposite Import Format for all Data (.kmData)
IconAuxiliary Tools
IconComments

Common Parameters across Regional TACs from Different Studies

IconPKIN Menu
IconCommon Parameters across Regional TACs from Different Studies

Common Parameters across Regional TACs of a Single Study

IconCommon Parameters across Regional TACs of a Single Study
IconBlood Delay Fitting
IconMonte Carlo Simulations

Comparison of Model Curves for a Region

IconModel Fitting History
IconComparison of Model Curves for a Region

Comparison using two PKIN Windows

IconComparison of Model Curves for a Region
IconComparison using two PKIN Windows

Compartment Model with 2 Eigenvalues

Compartment Model with 3 Eigenvalues

IconCompartment Model with 3 Eigenvalues
IconCompartment Model with 2 Eigenvalues
IconGamma Function plus two Decaying Exponentials

Compartment Models

IconCompartment Models
IconCompartment Models

Compartment Models for Cardiac Perfusion PET

Composite Import Format for all Data (.kmData)

IconImport of Tissue Time-Activity Data
IconComposite Import Format for all Data (.kmData)
IconBatch Mode

Configuration and Fitting of Kinetic Tissue Models

IconPlasma
IconParent/Plasma Fraction
IconConfiguration and Fitting of Kinetic Tissue Models
IconPlasma/Whole-blood Fraction

Convenience Tools

Copy Operations

Coupled Fitting for Improving Parameter Estimates

IconProcessing Overview
IconCoupled Fitting for Improving Parameter Estimates
IconIrreversible 2-Tissue Compartment Model, K1/k2, Flux
IconCoupled fitting for Determination of k2' in Reference Tissue Models

Curve Display

IconGeneral Curve Display Functionality
IconCurve Display

Curve Layout

- D -

Data Import from VOIs

Data Saving

IconPKIN Menu
IconData Saving

Data Transfer for Parametric Mapping in PKIN

Data Units

Decaying Exponentials

IconLinear Activity Interpolation
IconDecaying Exponentials
IconCompartment Model with 3 Eigenvalues
IconCompartment Model with 2 Eigenvalues

Default Model Configurations and Configuration Sets

IconDefault Model Configurations and Configuration Sets
IconDefault Model Configurations and Configuration Sets

Determination of k2' for Models Assuming a Pre-determined k2' Value

IconCoupled fitting for Determination of k2' in Reference Tissue Models
IconSimplified Reference Tissue Model 2 (SRTM2)
IconLogan's Reference Tissue Model based on Average k2'
IconIchise's Multilinear Reference Tissue Model 2 (MRTM2)

Disable Measurements for Removing Outliers or Shortening the Fitted Data Segment

Dispersion Calibration in PKIN

IconDispersion Calibration in PKIN
IconCalibration: Step-Up
IconCalibration: Step-Down

Dispersion Correction in PKIN

IconDispersion Correction in PKIN
IconCalibration: Correction

Dispersion Correction Methodology

IconDispersion Correction Methodology
IconDispersion Calibration in PKIN

Dispersion Correction of Automated Blood Samples

IconWhole Blood
IconDispersion Correction of Automated Blood Samples
IconInterpolation Functions for Whole-Blood and Plasma Activity

- E -

Edit Data and Create New Curves

IconImport of Tissue Time-Activity Data
IconKinetic Model Configuration
IconAuxiliary Tools
IconEdit Data and Create New Curves
IconVoxel-wise TAC modeling in PKIN
IconCumulated Activity (OLINDA, IDAC)

Edit Patient and Change Isotope

IconResidual Weighting
IconAuxiliary Tools
IconEdit Data and Create New Curves
IconEdit Patient and Change Isotope
IconCumulated Activity (OLINDA, IDAC)

Editing Facilities

Exponential Plasma/Whole-blood Fraction

IconLinear Interpolation of Plasma/Whole-blood Fraction
IconExponential Plasma/Whole-blood Fraction

- F -

FDG 2-Tissue Compartment Model

File-based Data Import

Fitting and Residual Weighting

IconFitting and Residual Weighting
IconIterative Fitting Principle
IconResidual Weighting

Fitting Blood Shape Parameters and Tissue Parameters together

IconFitting Options on Extras Panel
IconFitting Blood Shape Parameters and Tissue Parameters together

Fitting Multiple Models

Fitting Options on Extras Panel

IconProcessing Overview
IconFitting Options on Extras Panel
IconParameter Sensitivity to Acquisition Duration
IconBatch Mode

Fitting Problems

Fix Parent/Plasma Fraction

Fix Plasma Fraction

Flumazenil Triple-injection Model

IconList of PKIN Compartment Models
IconFlumazenil Triple-injection Model
IconFlumazenil, HOT Input Curve
IconFlumazenil, COLD Input Curve

Flumazenil, COLD Input Curve

Flumazenil, HOT Input Curve

Fractal Dimension

IconNon-Compartmental Models
IconFractal Dimension

Full Reference Tissue Model

IconReference Tissue Models
IconFull Reference Tissue Model
IconSimplified Reference Tissue Model (SRTM)

- G -

Gamma Function

Gamma Function plus two Decaying Exponentials

General Assumptions in PKIN

General Curve Display Functionality

IconGeneral Curve Display Functionality
IconTissue Ratio Methods

Global Configuration with Config Button

- H -

Hill Function

IconHill Function
IconHill Function

- I -

Ichise Multilinear Analysis MA1

IconNon-Compartmental Models
IconIchise Multilinear Analysis MA1
IconIchise Multilinear Analysis MA2

Ichise Multilinear Analysis MA2

IconNon-Compartmental Models
IconIchise Multilinear Analysis MA2

Ichise's Multilinear Reference Tissue Model (MRTM)

IconReference Tissue Models
IconIchise's Multilinear Reference Tissue Model (MRTM)

Ichise's Multilinear Reference Tissue Model 2 (MRTM2)

IconReference Tissue Models
IconIchise's Multilinear Reference Tissue Model 2 (MRTM2)

Ichise's Original Multilinear Reference Tissue Model (MRTM0)

IconReference Tissue Models
IconIchise's Original Multilinear Reference Tissue Model (MRTM0)
IconIchise's Multilinear Reference Tissue Model (MRTM)

Import of Blood Data

Import of Tissue Time-Activity Data

IconPKIN Menu
IconImport of Tissue Time-Activity Data

Input Curve

IconInput Curve
IconPreparation of Blood Data

Interpolation Functions for Parent/Plasma Fraction

IconParent/Plasma Fraction
IconInterpolation Functions for Parent/Plasma Fraction

Interpolation Functions for Plasma/Whole-Blood Fraction

IconPlasma
IconInterpolation Functions for Plasma/Whole-Blood Fraction
IconPlasma/Whole-blood Fraction

Interpolation Functions for Whole-Blood and Plasma Activity

IconPlasma
IconInterpolation Functions for Whole-Blood and Plasma Activity

Interpolation of Blood Data

Introduction to Modeling in PET

Irreversible 2-Tissue Compartment Model

IconList of PKIN Compartment Models
IconIrreversible 2-Tissue Compartment Model

Irreversible 2-Tissue Compartment Model, K1/k2, Flux

IconList of PKIN Compartment Models
IconIrreversible 2-Tissue Compartment Model, K1/k2, Flux

Iterative Fitting Principle

Ito Plot

- K -

Kinetic Model Configuration

Kinetic Model Fitting

IconWhole Blood
IconKinetic Model Fitting

- L -

Linear Activity Interpolation

Linear Function

Linear Interpolation Fraction

Linear Interpolation of Plasma/Whole-blood Fraction

Linear Simplified Reference Tissue Model (LSRTM)

List of PKIN Compartment Models

Local PKIN Configuration

IconLocal PKIN Configuration
IconPKIN Menu
IconCurve Layout
IconData Units

Logan Plot

IconIchise's Original Multilinear Reference Tissue Model (MRTM0)
IconIchise's Multilinear Reference Tissue Model (MRTM)
IconIchise's Multilinear Reference Tissue Model 2 (MRTM2)
IconNon-Compartmental Models
IconLogan Plot
IconIchise Multilinear Analysis MA1
IconIchise Multilinear Analysis MA2

Logan's Reference Tissue Model based on Average k2'

IconReference Tissue Models
IconLogan's Reference Tissue Model based on Average k2'

- M -

MLAIR (Multiple Linear Analysis for Irreversible Radiotracers)

Model based Image Panel

Model Filtering

IconKinetic Model Configuration
IconModel Filtering
IconFitting Multiple Models

Model Fitting History

IconProcessing Overview
IconData Saving
IconModel Fitting History
IconFitting Multiple Models
IconParameter Comparison across Regions (PKIN Parameters Explorer)
IconComparison of Model Curves for a Region
IconComparison using two PKIN Windows
IconMonte Carlo Simulations
IconBatch Mode

Model Parameter Propagation/Conversion during Model Switching

IconDefault Model Configurations and Configuration Sets
IconModel Parameter Propagation/Conversion during Model Switching
IconFitting Options on Extras Panel
IconIrreversible 2-Tissue Compartment Model, Flux
IconIrreversible 2-Tissue Compartment Model, K1/k2, Flux

Model Parameters

Model Structure

IconModel Structure
IconModel Parameter Propagation/Conversion during Model Switching

Modeling in Batch Pipeline

Monte Carlo Simulations

IconProcessing Overview
IconResidual Weighting
IconMonte Carlo Simulations

Multi-linear Reference Tissue Model for [11C]-MP4A (RLS)

IconReference Tissue Models
IconMulti-linear Reference Tissue Model for [11C]-MP4A (RLS)

- N -

New Topic (10)

New Topic (8)

IconEdit Data and Create New Curves
IconCumulated Activity (OLINDA, IDAC)

Non-Compartmental Models

IconIntroduction to Modeling in PET
IconNon-Compartmental Models

- O -

Original Image Panel

- P -

Parameter Comparison across Regions (PKIN Parameters Explorer)

IconModel Fitting History
IconParameter Comparison across Regions (PKIN Parameters Explorer)
IconAuxiliary Tools

Parameter Restriction

IconParameter Restriction
IconFitting Options on Extras Panel

Parameter Sensitivity to Acquisition Duration

IconModel Fitting History
IconParameter Sensitivity to Acquisition Duration

Parameters Aggregation

IconPKIN Menu
IconData Saving
IconFitting Multiple Models
IconParameters Aggregation

Parametric Mapping Interface

Parametric Maps Panel

IconParametric Mapping Interface
IconParametric Maps Panel

Parent/Plasma Fraction

IconPKIN Menu
IconParent/Plasma Fraction
IconFix Parent/Plasma Fraction
IconLinear Interpolation Fraction
Icon1-Exponential
Icon2-Exponentials
Icon3-Exponentials
IconHill Function
IconWatabe Function
IconPower-Damped Exponentials
IconSigmoid Function

Partial Saturation Method, Data-driven

Patlak Plot

IconFDG 2-Tissue Compartment Model
IconIrreversible 2-Tissue Compartment Model
IconIrreversible 2-Tissue Compartment Model, Flux
IconIrreversible 2-Tissue Compartment Model, K1/k2, Flux
IconNon-Compartmental Models
IconPatlak Plot
IconMLAIR (Multiple Linear Analysis for Irreversible Radiotracers)

Patlak Reference Tissue Model

PKIN Data Processing

PKIN for Parametric Mapping

IconPKIN Menu
IconPKIN for Regional Parametric Mapping

PKIN Menu

PKIN Reference

IconCalculation of the Model Curve
IconPKIN Reference

Plasma

IconPKIN Menu
IconPlasma

Plasma/Whole-blood Fraction

IconFix Plasma Fraction
IconLinear Interpolation of Plasma/Whole-blood Fraction
IconExponential Plasma/Whole-blood Fraction
IconHill Function
IconWatabe Function
IconSigmoid Function
IconLinear Function
IconPlasma/Whole-blood Fraction

PMOD Copyright Notice

PMOD Kinetic Modeling Tool (PKIN)

Power-Damped Exponentials

Preparation of Blood Data

IconGeneral Assumptions in PKIN
IconPreparation of Blood Data
IconCard. NH3 (2 Compartments, K1/k2)
IconLinear Activity Interpolation
IconDecaying Exponentials
IconCompartment Model with 3 Eigenvalues
IconCompartment Model with 2 Eigenvalues
IconGamma Function
IconGamma Function plus two Decaying Exponentials
IconFix Plasma Fraction
IconLinear Interpolation of Plasma/Whole-blood Fraction
IconExponential Plasma/Whole-blood Fraction
IconHill Function
IconWatabe Function
IconSigmoid Function
IconLinear Function
IconFix Parent/Plasma Fraction
IconLinear Interpolation Fraction
Icon1-Exponential
Icon2-Exponentials
Icon3-Exponentials
IconHill Function
IconWatabe Function
IconPower-Damped Exponentials
IconSigmoid Function

Processing Overview

- R -

Reference Models

IconReference Tissue Models
IconReference Models
IconReference Tissue Models

Reference Tissue Models

References

RE-GP Analysis

Residual Weighting

IconResidual Weighting
IconMonte Carlo Simulations
IconEdit Patient and Change Isotope

- S -

SE Maps Panel

Sigmoid Function

IconSigmoid Function
IconSigmoid Function

Simplified Reference Tissue Model (SRTM)

IconReference Tissue Models
IconSimplified Reference Tissue Model (SRTM)
IconSimplified Reference Tissue Model 2 (SRTM2)
IconLinear Simplified Reference Tissue Model (LSRTM)

Simplified Reference Tissue Model 2 (SRTM2)

IconReference Tissue Models
IconSimplified Reference Tissue Model 2 (SRTM2)

Simulation of Bolus/Infusion Tracer Application

Special Processing Types

Spectral Analysis (SA)

IconSpectral Analysis (SA)
IconSpectral Analysis, vB
IconSpectral Analysis SAIF

Spectral Analysis SAIF

Spectral Analysis, vB

Starting the Kinetic Modeling Tool

Statistical Criteria for Comparing Models

Synthetic Data Generation

Synthetic Imaging Study for PXMOD Tests

IconPKIN Menu
IconSynthetic Imaging Study for PXMOD Tests

Synthetic Modeling Study for PKIN

IconPKIN Menu
IconSynthetic Modeling Study for PKIN

- T -

Time-Activity Curve Generation with Transfer to PKIN

IconData Import from VOIs
IconTime-Activity Curve Generation with Transfer to PKIN

Tissue Ratio Methods

IconNon-Compartmental Models
IconTissue Ratio Methods

Tissue/Plasma Ratio

Tracer Retention Fraction

IconNon-Compartmental Models
IconTracer Retention Fraction

- U -

User Interface

- V -

Visualization of Parameter Effect

Voxel-wise TAC modeling in PKIN

- W -

Watabe Function

IconWatabe Function
IconWatabe Function

Watabe's Reference Tissue Model with 2 Compartments

IconReference Tissue Models
IconWatabe's Reference Tissue Model with 2 Compartments

Water PET Model with Flow and Dispersion

IconList of PKIN Compartment Models
IconWater PET Model with Flow and Dispersion

Whole Blood

IconPKIN Menu
IconWhole Blood
IconPlasma
IconBlood Delay Fitting
IconInterpolation Functions for Whole-Blood and Plasma Activity