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PXMOD is the main PMOD tool for parametric mapping and provides a streamlined workflow for the data analysis. However, the modeling incorporated in PXMOD features a limited set of models and is not aimed at detailed interactive modeling of TACs from individual pixels. PKIN offers an alternative for generating parametric maps of limited image sub-volumes, leveraging interactive modeling with the full model set as described below. For instance, the heterogeneity of a tumor might be investigated using the PKIN-based parametric mapping approach.