The configuration of PKIN can be adjusted by Kinetic/Settings/Modify
or using the configuration button 
from the status line. It opens the following dialog with the current definitions, which can be modified. The Paths tab allows setting the initial data paths of file-based loading as well as the file extension filters.
The Display pane gives access to the settings of the initial PKIN appearance and the appearance of the report page.
The PKIN pane shows the current models of tissue, whole blood, plasma and the parent fraction with their respective default parameters. Changing the parameters here and saving will establish new default parameters.
The next section allows specifying the time and value units of data loaded from text files. If the header lines in the data file do not contain valid units, these units are applied to the imported data.
The lower section serves for modifying the layout:
▪Curve controls position allows displaying the curve controls to the Right, Left or at the Bottom. Their purpose is to optimize the layout depending on the display aspect ratio. Left and Right are recommended for wide screen systems, otherwise Bottom.
▪Center model parameters display: If this box is enabled the parameters area is centered vertically within the available space.
▪HD curve model display: If this box is checked the model curves are calculated for display purposes at many intermediate points, not just at the measurement times. The result is a smooth appearance of the model curves. However, when exporting the model curves, these interpolated points may be disturbing. Note that for the fitting only the original acquisition times are used.